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- DOI 10.18231/j.ijos.2025.029
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CrossMark
Behaviour distal radius giant cell tumour: Contemporary and innovative management of an uncommon presentation: A case report
- Author Details:
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Mauricio Ramos Suaza *
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Gabriel Narváez Rodriguez
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Andres Ramirez Jaramillo
Mauricio Ramos Suaza *
Gabriel Narváez Rodriguez
Andres Ramirez Jaramillo
Giant cell tumour (GCT) of the distal radius is an uncommon benign but locally aggressive bone neoplasm that poses a surgical challenge due to its anatomical location and potential for joint destruction. Its management in advanced stages, such as Campanacci grade III, often requires en bloc resection followed by structural reconstruction to restore function and stability. We report the case of a 36-year-old woman diagnosed with a Campanacci III GCT of the distal radius. The patient underwent en bloc tumour resection followed by reconstruction using a structural allograft and dynamic compression plate fixation. Additionally, an ulnar osteotomy and screw fixation were performed to stabilize the distal radioulnar joint. Postoperative radiographs confirmed appropriate graft-host integration. Clinically, the patient experienced mild, non-disabling pain and preserved wrist range of motion and distal radioulnar joint stability during follow-up. This case highlights the efficacy of using structural allografts in the management of advanced GCT of the distal radius. This approach allows for joint preservation, functional recovery, pain control, and avoids donor site morbidity associated with autografts. Although infrequent, such tumours require individualized, multidisciplinary management supported by detailed surgical planning.
Keywords: Giant cell tumour, Distal radius, En bloc resection, Structural allograft, Orthopaedic oncology, Bone reconstruction.
References
- Estrada-Villaseñor EG, Linares-González LM, Delgado-Cedillo EA, González-Guzmán R, Rico-Martínez G. Prevalencia y características clínico-patológicas del tumor de células gigantes. Acta Ortop Mex. 2015;29(6):295–8.
- Hess MC, Kafchinski L, Ransom E. Giant Cell Tumor of the Distal Radius: A Review. Orthop Clin North Am. 2023;54(1):75–88.
- Palmerini E, Picci P, Reichardt P, Downey G. Malignancy in Giant Cell Tumor of Bone: A Review of the Literature. Technol Cancer Res Treat. 2019;18(1):1–8.
- Chobpenthai T, Poosiripinyo T, Warakul C. Reconstruction after en bloc resection of a distal radius tumor. An updated and concise review. Orthop Res Rev. 2023;15:151–64.
- Bianchi G, Donati D, De La Signora E, Mercuri M. Osteoarticular allograft reconstruction of the distal radius after bone tumour resection. J Hand Surg Br. 2005;30(3):264–70.
- Scoccianti G, Campanacci DA, Beltrami G, Caldora P, Capanna R. The use of osteo-articular allografts for reconstruction after resection of the distal radius for tumour. J Bone Joint Surg Br. 2010;92(12):1690–4.
- Wang T, Chan CM, Yu F, Li Y, Niu X. Does wrist arthrodesis with structural iliac crest bone graft after wide resection of distal radius giant cell tumor result in satisfactory function and local control? Clin Orthop Relat Res. 2017;475(3):767–75.
- Szabo RM, Anderson KA, Chen JL. Functional outcome of en bloc excision and osteoarticular allograft replacement with the Sauve- Kapandji procedure for Campanacci grade 3 giant-cell tumor of the distal radius. J Hand Surg Am. 2006;31(8):1340–8.
- Liu W, Wang B, Zhang S, Li Y, Hu B, Shao Z. Wrist reconstruction after en bloc resection of bone tumors of the distal radius. Orthop Surg. 2021;13(2):376–83.
- Duan H, Zhang B, Yang HS, Liu YH, Zhang WL, Min L, et al. Functional outcome of en bloc resection and osteoarticular allograft reconstruction with locking compression plate for giant cell tumor of the distal radius. J Orthop Sci. 2013;18(4):599–604.
- Kocher MS, Gebhardt MC, Mankin HJ. Reconstruction of the distal aspect of the radius with use of an osteoarticular allograft after excision of a skeletal tumor. J Bone Joint Surg Am. 1998;80(3):407–
- Clarkson PW, Sandford K, Phillips AE, Pazionis TJC, Griffin A, Wunder JS, et al. Functional results following vascularized versus nonvascularized bone grafts for wrist arthrodesis following excision of giant cell tumors. J Hand Surg Am. 2013;38(5):935–40.
- Sano K, Kimura K, Ozeki S. Vascularized iliac bone lining in downgraded treatment of Campanacci grade III giant cell tumor of the distal radius. J Hand Surg Asian Pac. 2018;23(2):255–8.